Plan estratégico para la gestión de residuos sólidos en una municipalidad distrital de Chiclayo

La investigación se caracterizó por la búsqueda de reformas necesarias dentro de la gestión de residuos sólidos municipales, para ello se propuso el objetivo general fue proponer un plan estratégico para mejorar la gestión de residuos sólidos en una municipalidad distrital de Chiclayo. La presente investigación cuenta con diseño no experimental, con una muestra de 378 pobladores, recolectando los datos por medio del cuestionario, la confiabilidad Alfa de Cronbach es de 0.815. Se tuvo como resultado principal que existe deficiencia en la gestión de residuos sólidos, en donde presenta el 52.60% de los usuarios carecen de información acerca de los procesos de recolección y segregación final de los residuos, por lo que se identificaron las características requeridas para el diseño de un plan estratégico, el cual se centra en la sensibilización de los pobladores y trabajadores de la municipalidad, fue validado por tres expertos. Asimismo, se tiene como fin motivar la participación de las autoridades, trabajadores y pobladores generando un compromiso para contribuir en la disminución de la contaminación ambiental. Se concluye que una propuesta de un plan podría mejorar la gestión de residuos sólidos en la comunida

Hexaferrite-based permanent magnets with upper magnetic properties by cold sintering process via a non-aqueous solvent

The incessant technological pursuit towards a more sustainable and green future depends strongly on permanent magnets. At present, their use is widespread, making it imperative to develop new processing methods that generate highly competitive magnetic properties reducing the fabrication temperatures and costs. Herein, a novel strategy for developing dense sintered magnets based on Sr-hexaferrites with upper functional characteristics is presented. An innovative cold sintering approach using glacial acetic acid as novelty, followed by a post-annealing at 1100 {\deg}C, achieves a densification of the ceramic magnets of 92% with respect to the theoretical density and allows controlling the particle growth. After the cold sintering process, a fraction of amorphous SrO is identified, in addition to a partial transformation to {\alpha}-Fe2O3 as secondary crystalline phase. 46 wt% of SrFe12O19 remains, which is mostly recuperated after the post-thermal treatment. These findings do not significantly modify the final structure of ferrite magnets, neither at short- nor long-range order. The innovative process has a positive impact on the magnetic properties, yielding competitive ferrite magnets at lower sintering temperatures with an energy efficiency of at least 25%, which opens up a new horizon in the field of rare-earth free permanent magnets and new possibilities in other applications

Carbosilane dendritic nanostructures, highly versatile platforms for pharmaceutical applications

Dendrimers are multifunctional molecules with well-defined size and structure due to the step-by-step synthetic procedures required in their preparation. Dendritic constructs based on carbosilane scaffolds present carbon-carbon and carbon-silicon bonds, which results in stable, lipophilic, inert, and flexible structures. These properties are highly appreciated in different areas, including the pharmaceutical field, as they can increase the interaction with cell membranes and improve the therapeutic action. This article summarizes the most recent advances in the pharmaceutical applications of carbosilane dendritic molecules, from therapeutics to diagnostics and prevention tools. Dendrimers decorated with cationic, anionic, or other moieties, including metallodendrimers; supramolecular assemblies; dendronized nanoparticles and surfaces; as well as dendritic networks like hydrogels are described. The collected examples confirm the potential of carbosilane dendrimers and dendritic materials as antiviral or antibacterial agents; in therapy against cancer, neurodegenerative disease, or oxidative stress; or many other biomedical applications.This article is categorized under:Nanotechnology Approaches to Biology > Nanoscale Systems in BiologyTherapeutic Approaches and Drug Discovery > Nanomedicine for Infectious DiseaseTherapeutic Approaches and Drug Discovery > Nanomedicine for Oncologic DiseaseMinisterio de Economía y CompetitividadComunidad de MadridJunta de Comunidades de Castilla-La ManchaUniversidad de Alcal

Organization and characterization of the promoter elements of the rRNA pperons in the slow-growing pathogen mycobacterium kumamotonense

The slow-growing, nontuberculous mycobacterium Mycobacterium kumamotonense possesses two rRNA operons, rrnA and rrnB, located downstream from the murA and tyrS genes, respectively. Here, we report the sequence and organization of the promoter regions of these two rrn operons. In the rrnA operon, transcription can be initiated from the two promoters, named P1 rrnA and PCL1, while in rrnB, transcription can only start from one, called P1 rrnB. Both rrn operons show a similar organization to the one described in Mycobacterium celatum and Mycobacterium smegmatis. Furthermore, by qRT-PCR analyses of the products generated from each promoter, we report that stress conditions such as starvation, hypoxia, and cellular infection affect the contribution of each operon to the synthesis of pre-rRNA. It was found that the products from the PCL1 promoter of rrnA play a pivotal role in rRNA synthesis during all stress conditions. Interestingly, the main participation of the products of transcription from the P1 promoter of rrnB was found during hypoxic conditions at the NRP1 phase. These results provide novel insights into pre-rRNA synthesis in mycobacteria, as well as the potential ability of M. kumamotonense to produce latent infection

Descomposición de la capa de hojarasca de diferentes especies perennifolias y caducifolias

Las hojarascas de las especies caducifolias y perennifolias presentan procesos diferenciales de descomposición, debidos, en gran parte, a las diferencias en su composición químic

Body silhouettes as a tool to reflect obesity in the past

Life course data on obesity may enrich the quality of epidemiologic studies analysing health consequences of obesity. However, achieving such data may require substantial resources. We investigated the use of body silhouettes in adults as a tool to reflect obesity in the past. We used large population-based samples to analyse to what extent self-reported body silhouettes correlated with the previously measured (9-23 years) body mass index (BMI) from both measured (European Community Respiratory Health Survey, N = 3 041) and self-reported (Respiratory Health In Northern Europe study, N = 3 410) height and weight. We calculated Spearman correlation between BMI and body silhouettes and ROC-curve analyses for identifying obesity (BMI ≥30) at ages 30 and 45 years. Spearman correlations between measured BMI age 30 (±2y) or 45 (±2y) and body silhouettes in women and men were between 0.62-0.66 and correlations for self-reported BMI were between 0.58-0.70. The area under the curve for identification of obesity at age 30 using body silhouettes vs previously measured BMI at age 30 (±2y) was 0.92 (95% CI 0.87, 0.97) and 0.85 (95% CI 0.75, 0.95) in women and men, respectively; for previously self-reported BMI, 0.92 (95% CI 0.88, 0.95) and 0.90 (95% CI 0.85, 0.96). Our study suggests that body silhouettes are a useful epidemiological tool, enabling retrospective differentiation of obesity and non-obesity in adult women and men

Modelo de gestión socioempresarial solidario: Lineamientos conceptuales de áreas temáticas.

Este libro es parte de la experiencia teórico-práctica de UNIMINUTO, liderada por al Escuela de Economía Solidaria de la Facultad de Ciencias Empresariales. Dicha experiencia surge mediante un convenio estratégico para beneficiar, de manera sustancial, a las organizaciones solidarias con el fin de que puedan cumplir con sus múltiples funciones, además de la económica; es decir, en la producción de bienes y servicios en pro de mejorar la calidad de vida de sus comunidades sujetos de acción. El presente texto evidencia la segunda fase, de una investigación más amplia, y se enfoca en el desarrollo conceptual de las áreas temáticas de trabajo para un modelo de gestión socioempresarial solidario. Por tanto, en estas páginas el lector encontrará parte del desarrollo del modelo de gestión socioempresarial solidario. Se presenta como una contribución para las organizaciones solidarias, las cuales vienen siento gestionadas bajo los parámetros de las empresas de capital, que desnaturaliza sus funciones socioeconómicas, culturales, ambientales y de participación solidaria. No obstante, lo que se busca es fomentar una economía al servicio del ser humano, y no el ser humano al servicio de la economía. Se espera seguir avanzando en el desarrollo de estás áreas temáticas apoyados con trabajo con las organizaciones del sector solidario